First of all, artefact is a variant of artifact. Structure refers to bigger buildings, artefact relates to smaller hand-made objects. Structure means the way in which parts are arranged or put together. It refers to something constructed but which is not hand-made, while artefact is something hand-made in order to use it or something which is given shape by man. In a somewhat abstract sense, structure means the pattern or the system of belief or relationship in society. It also means a complex system considered from the aspect of the whole. These terms can be found in biology, as well. In biological sense, structure refers to the arrangement of the tissues or organs, while artefact means a structure seen in tissue after death, so it is something that is normally not present in a living tissue.
